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The Week 12 NFL slate begins on Thursday, Nov. 21 with Steelers vs. Browns and runs through Ravens vs.
Chargers on Monday Night Football on Nov. 25. Below, we preview some of the week's biggest games and provide NFL Week 12 odds for every game.
NFL Week 12 betting odds: Moneyline, spread & total for every Week 12 NFL game Week 12 Thursday Night Football odds: Pittsburgh Steelers (-4.5) at Cleveland Browns - Nov. 21, 8:15 p.
m. ET The first-place Pittsburgh Steelers (8-2) visit the division-rival Cleveland Browns (2-8) on Thursday Night Football looking for a sixth straight victory. Pittsburgh took down the Ravens on Sunday with six field goals and elite defense, forifying their AFC North lead in the process.
The Steelers are now the NFL's best against-the-spread team at 8-2 according to TeamRankings , while Cleveland has covered just three of 10 games. Week 12 NFL betting odds: Detroit Lions (-8) at Indianapolis Colts - Nov. 24, 1 p.
m. ET The Detroit Lions (9-1) showed no mercy against the Jaguars in Week 11, winning 52-6 for an eighth straight victory and an NFC-best 9-1 record. With Kansas City's loss to Buffalo, the Lions are now tied for the top record in the league as well.
They'll visit the Indianapolis Colts (5-6), a team hanging on the fringes of the AFC Wild Card picture following Sunday's one-point road win over the Jets. QB Anthony Richardson shined with over 300 total yards and three scores including two on the ground. This matchup pits two of the the best against-the-spread teams in the league against one another.
Detroit is 8-2 and the Colts are 8-3 ATS. NFL Week 12 odds: Arizona Cardinals (+1) at Seattle Seahawks - Nov. 24, 4:25 p.
m. ET The NFC West is absolute chaos this season with the Arizona Cardinals (6-4) on top and the other three teams at 5-5, including the Seattle Seahawks after Geno Smith's late heroics put Seattle past San Francisco in Week 11. Seattle is a slight favorite in this game but for what it's worth, the Cardinals had a bye last week and have won four games in a row.
Seattle is also just 2-4 at home this season. NFL Week 12 betting odds: NFL betting lines for all Week 12 games Check out Week 12 NFL betting lines for each game on the slate below: You must be over 21 to play. Gambling Problem? Call 1-800-522-4700.
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