Historic Achievement at NIMS Hyderabad: First-Ever TMVR Performed Successfully

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For the first time in the history of Nizam’s Institute of Medical Sciences (NIMS) in Hyderabad, a rare and complex Transcatheter Mitral Valve Replacement (TMVR) procedure was performed successfully on a 56-year-old patient suffering from severe mitral stenosis due to Mitral Annular Calcification (MAC). The patient, who is also suffering from hypertension, diabetes, and chronic kidney disease (CKD) requiring maintenance hemodialysis, was deemed high-risk for a conventional surgical mitral valve replacement. Faced with this challenge, the expert cardiology team at NIMS sought alternative, cutting-edge treatment options.

Under the leadership of Dr. B. Srinivas, Professor and Head of the Department of Cardiology, and his skilled team comprising Dr.



Manikrishna, Dr. Abhinay Reddy, and Dr. K.

Anurag, the patient underwent a successful TMVR procedure on November 19. The team also employed the LAMPOON procedure - an advanced technique designed to prevent obstruction to blood flow post-implantation by cutting a portion of the native valve. TMVR is a state-of-the-art, minimally invasive procedure that replaces a diseased mitral valve without the need for open-heart surgery.

Instead, the new valve is implanted via a blood vessel in the leg, ensuring a faster and safer recovery. Performing TMVR in a patient with mitral annular calcification, where excess calcium deposits significantly complicate the process, is exceedingly rare and has only been successfully attempted a handful of times globally. The patient’s remarkable recovery further underscores the success of this pioneering procedure.

Within two days, he was walking and resuming normal household activities. By day four, he was discharged from the hospital. This groundbreaking achievement highlights the advanced capabilities of the NIMS cardiology team and marks a new milestone in the institute’s history.

The success of this rare procedure not only brings hope to high-risk patients with complex cardiac conditions but also solidifies NIMS as a leader in cutting-edge medical interventions..