All-Pro RB Christian McCaffrey will miss the 49ers opener against the Jets with a calf injury

SANTA CLARA, Calif. (AP) — All-Pro running back will miss the season opener against the because of a sore calf and Achilles tendon that has hampered him all summer. McCaffrey got hurt early in training camp and missed four weeks of practice before returning to the field last week.

He was listed as questionable and said he expected to play Monday night. But he was a surprise scratch for the game. is expected to take the load at running back in McCaffrey’s place.



McCaffrey led the NFL last season with 2,023 yards from scrimmage and was tied for the league lead with 21 touchdowns, winning AP Offensive Player of the Year. San Francisco also activated All-Pro left tackle to the 53-man roster after his lengthy contract holdout. was released to make room.

The Niners also promoted defensive end and safety from the practice squad to play against the Jets. The other inactive players for San Francisco are defensive end (knee), safety (knee), linebacker (ankle), offensive lineman and cornerback Darrell Luter. is the emergency third quarterback.

The Jets also made several roster moves Monday. They signed offensive lineman and linebacker to the active roster and placed linebacker on injured reserve. Tight end and defensive lineman were promoted from the practice squad for the game.

New York also signed running back to the practice squad. The inactive players for the Jets are offensive lineman , running back , tackler , tight end Brenden Bates, defensive lineman , defensive lineman Leonard Taylor and cornerback . ___ AP NFL: Josh Dubow, The Associated Press.