Activists sound alarm bells as Gilead seeks rights over HIV drug

Lenacapavir, a very expensive drug, is not available in India and many other countries. If the Indian Patent Office clears Gilead's patent applications, generic drug makers in India will not be allowed to produce its affordable forms.

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NEW DELHI: Activists in India are opposing US pharmaceutical major Gilead Sciences ' patent applications on HIV prevention drug lenacapavir , in a bid to make the ground-breaking treatment affordable for all. Lenacapavir, a very expensive drug, is not available in India and many other countries. If the Indian Patent Office clears Gilead's patent applications, generic drug makers in India will not be allowed to produce its affordable forms.

This week, the patent office is likely to hear the objections of Sankalp Rehabilitation Trust--a civil society organisation which works with people vulnerable to HIV- to Gilead's patent applications regarding lenacapavir which, if granted, will extend the company's monopoly over lenacapavir. Gilead has several patent applications in India on lenacapavir. Two of these applications, filed in 2020, seek patents on the choline and sodium salt of the drug lenacapavir.



Sankalp contends that Gilead's claims on the salt forms of lenacapavir are not innovative. It had opposed Gilead's patent applications in 2021 on the ground that the drug has a previously known compound. Indian patent law prohibits "evergreening", a practice by which pharmaceutical companies seek patents on routine modifications to extend their drug monopolies beyond the standard 20-year period.

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C.P. Gupta, Professor: Department of Finance and Business Economics, University of Delhi View Program Marketing Performance Marketing for eCommerce Brands By - Zafer Mukeri, Founder- Inara Marketers View Program "Granting these patents, which would last until August 2038, could hinder access to affordable generic versions of lenacapavir," Eldred Tellis , director of Sankalp Rehabilitation Trust , said in a statement.

"Affordable generic HIV medicines have been crucial in keeping people alive globally, including in India." Lenacapavir is administered as twice-yearly injections and has garnered attention for its potential in HIV prevention after multiple clinical trials demonstrated superior efficacy to standard oral preventative medicines, known as pre-exposure prophylaxis (PrEP). According to UNAIDS, the new HIV drug can play a crucial role in ending AIDS if all have access.

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