A study identified 6 types of depression. Here’s why that matters

Scientists may be a step closer to that reality, thanks to new research that has identified six subtypes — or 'biotypes' — of major depression via brain imaging combined with machine learning.

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For some people with depression, finding the right medication can be a process of trial and error lasting for months or even years, which can worsen symptoms. But what if doctors, when diagnosing someone with depression, could assess exactly how depression is affecting a patient’s brain and prescribe a treatment that gets it right the first time? The information you need to know, sent directly to you: Download the CTV News App Scientists may be a step closer to that reality, thanks to new research that has identified six subtypes — or “biotypes” — of major depression via brain imaging combined with machine learning. The study, published Monday in the journal Nature Medicine , also tested how three of those biotypes responded to different antidepressants and therapies.

“There are currently no tests available to help pinpoint what type of depression (people) have, or, I think especially importantly, what treatment might be most suitable for them,” said Dr. Leanne Williams, the study’s senior author and the Vincent V.C.



Woo Professor of Psychiatry and Behavioral Sciences at the Stanford University School of Medicine in California. “The current situation is we rely on a person to tell us what they’re experiencing and for the physician or therapist to observe symptoms and come to a diagnosis.” About 280 million people worldwide and 26 million people in the United States have depression, which is a leading cause of disability.

Some 30 per cent to 40 per cent o.